Cancer genetic and environmental factors, Cancerul colorectal – viziuni actuale asupra evoluţiei clinice


Cancer – from etilogy to therapeutic approaches

Selected References These references are in PubMed. This may not be the complete list of references from this article.

cancer genetic and environmental factors

Oxygen activation by cytochrome P Annu Rev Biochem. The molecular biology of cytochrome Ps. Pharmacol Rev.

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The P superfamily: update on new sequences, gene mapping, and recommended nomenclature. DNA Cell Biol. Evolution of cytochrome P proteins.

  1. Ничего более абсурдного Сьюзан слышать еще не доводилось.

  2. Он показался ему смутно знакомым.

  3. Невозможно.

  4. Сьюзан понимала, что сегодня любопытство Хейла может привести к большим неприятностям, поэтому быстро приняла решение.

  5. Он должен быть .

  6. Brasov Medical Journal- Home
  7. Вскоре спуск закончился, переключились какие-то шестеренки, и лифт снова начал движение, на этот раз горизонтальное.

  8. - У нас приказ.

Mol Biol Evol. Evolution of the P gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation.

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Trends Genet. Oxidation of toxic and carcinogenic chemicals by human cytochrome P enzymes.

Cancerul – de la etiologie la abordări terapeutice

Chem Res Toxicol. Constitutive and inducible expression of human cytochrome PIA1 in yeast Saccharomyces cerevisiae: an alternative enzyme source for in vitro studies. Biochem Biophys Res Commun.

Negreş Simona, As. The onset of cancer is the result of the interaction between a person genetic factors and the environmental factors and lifestyle. The major factors involved in cancer are: smoking, drinking alcohol, obesity, exposure to sunlight and some viral infections.

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. J Pharmacol Testicular cancer usmle Ther. Expression of a human liver cytochrome P protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae.

Mol Pharmacol.

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Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Identification of a new variant CYP2D6 allele lacking the codon encoding Lys possible association with the poor metabolizer phenotype. A tobacco smoke-derived nitrosamine, 4- methylnitrosamino 3-pyridyl butanone, is activated by multiple human cytochrome Ps including the polymorphic human cytochrome PD6.

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  • Human cytochromes P evolution and cDNA-directed expression.
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Mutagenic activation of 2-aminomethylimidazo[4,5-f]quinoline by complementary DNA-expressed human liver P Cancer Res. J Biol Chem. Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process.

Mutat Res. Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens. Cancer Detect Prev. Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P metabolically activate aflatoxin B1. Cancer genetic and environmental factors for gene mutation in a human lymphoblast line, AHH-1, competent for xenobiotic metabolism.

Human cytochromes P450: evolution and cDNA-directed expression.

A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. Molecular genetics of the debrisoquin-sparteine polymorphism.

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Clin Pharmacol Ther. Relevance of metabolic polymorphisms to human cancer genetic and environmental factors evaluation of epidemiologic evidence.

Hereditary Colorectal Cancer: Laura Valle · | Books Express

Identification of a human liver cytochrome P homologous to the major isosafrole-inducible cytochrome P in the rat. Purification and characterization of the human liver cytochromes P involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism. Identification and quantitation in human liver of cytochromes P analogous to rabbit cytochromes P forms 4 and 6. Metabolism of N-nitrosodialkylamines by human liver microsomes.